{"id":8836,"date":"2020-11-11T11:50:14","date_gmt":"2020-11-11T11:50:14","guid":{"rendered":"https:\/\/www.optometrists.org\/?page_id=8836"},"modified":"2022-03-22T10:22:37","modified_gmt":"2022-03-22T10:22:37","slug":"keratoconus-treatment-corneal-cross-linking","status":"publish","type":"page","link":"https:\/\/www.optometrists.org\/general-practice-optometry\/guide-to-eye-conditions\/guide-to-corneal-diseases\/keratoconus\/keratoconus-treatment-corneal-cross-linking\/","title":{"rendered":"Keratoconus Treatment: Corneal Cross-linking\u00a0"},"content":{"rendered":"<h2><b>Keratoconus is a progressive eye disease that weakens the cornea and changes its structure \u2014 leading to vision problems and even vision loss.\u00a0<\/b><\/h2>\n<p>The <a href=\"https:\/\/www.optometrists.org\/general-practice-optometry\/ocular-anatomy-the-front-of-the-eye\/\">cornea<\/a> is the outermost layer of the eye that covers the <a href=\"https:\/\/www.optometrists.org\/general-practice-optometry\/ocular-anatomy-the-front-of-the-eye\/\">pupil and iris<\/a>. In a healthy eye, the cornea is clear and dome-shaped.<\/p>\n<p>When <a href=\"https:\/\/www.optometrists.org\/general-practice-optometry\/guide-to-eye-conditions\/guide-to-corneal-diseases\/keratoconus\/\">keratoconus<\/a> develops, the cornea becomes thinner and begins to bulge into a cone-like shape. This irregular shape causes blurry and distorted vision as the light that enters the eye can no longer focus accurately onto the retina.<\/p>\n<p>Keratoconus generally causes mild to severe <a href=\"https:\/\/www.optometrists.org\/childrens-vision\/what-is-astigmatism\/\">astigmatism<\/a> and <a href=\"https:\/\/www.optometrists.org\/childrens-vision\/what-is-myopia\/\">nearsightedness<\/a>, but can also cause corneal swelling and scarring, and even vision loss.<\/p>\n<p>The most effective treatment for keratoconus is a procedure called corneal cross-linking.<\/p>\n<h2><b>What is corneal cross-linking?<\/b><\/h2>\n<p>Corneal cross-linking is the most <a href=\"https:\/\/www.optometrists.org\/general-practice-optometry\/guide-to-eye-conditions\/guide-to-corneal-diseases\/keratoconus\/\">effective treatment for keratoconus<\/a> as it strengthens the cornea by creating new bonds between the collagen fibers in the center of the cornea. These new bonds help to stiffen the cornea, support its circular shape and provide extra resistance to the effects of worsening keratoconus.<\/p>\n<p><b>Corneal cross-linking is the only treatment method that can stop keratoconus from worsening and reduce your chances of a corneal transplant later on in life.<\/b><\/p>\n<p>Cross-linking may also be used to treat severe corneal ulcers and infections that are unresponsive to antibiotics.<\/p>\n<p>In some cases, eye doctors may also recommend corneal cross-linking to strengthen the cornea prior to undergoing <a href=\"https:\/\/www.optometrists.org\/optical\/laser-refractive-surgery\/\">LASIK eye surgery<\/a>.<\/p>\n<h2><b>How is corneal cross-linking performed?<\/b><\/h2>\n<p>Cross linking is an in-office\u00a0 procedure that involves exposing the collagen fibers of the cornea to ultraviolet (UV) light.<\/p>\n<p>There are two different types of procedures:<\/p>\n<ul>\n<li style=\"font-weight: 400;\"><b>Epithelium-off (epi-off)<\/b>. During this procedure, the epithelium is completely removed to allow the collagen fibers to be fully exposed to the UV light.<\/li>\n<li style=\"font-weight: 400;\"><b>Epithelium-on (epi-on)<\/b>. This procedure is less invasive, as the epithelium is loosened, instead of removed completely.<\/li>\n<\/ul>\n<p>During both procedures, an eye drop of liquid riboflavin (vitamin B2) is applied to the surface of the eye. The eye is then exposed to the UV light at varying levels of time and intensity, to be absorbed by the cornea.<\/p>\n<p>The UV light functions to stabilize the collagen fibers in the cornea and slow the progression of disease.<\/p>\n<p><b>The epi-off procedure has proven to be 95 percent effective in stopping the progression of keratoconus.<\/b><\/p>\n<p>The epi-on procedure is also effective, though the long term effects are still being studied.<\/p>\n<p><strong>If you suspect you have an eye condition,\u00a0<a rel=\"noopener\" href=\"https:\/\/www.optometrists.org\/practice-search\/\" target=\"_blank\" data-saferedirecturl=\"https:\/\/www.google.com\/url?q=https:\/\/www.optometrists.org\/practice-search\/&amp;source=gmail&amp;ust=1626760891136000&amp;usg=AFQjCNFHnklrD-k7GckF_J6pnDwdBDDa9Q\">contact an eye doctor<\/a>\u00a0near you, who can diagnose and treat the condition.<\/strong><\/p>\n<p><strong>SEE RELATED:<\/strong> <a href=\"https:\/\/www.optometrists.org\/general-practice-optometry\/guide-to-eye-conditions\/guide-to-corneal-diseases\/keratoconus\/\">Keratoconus<\/a><\/p>\n\n\t<div class=\"practice-search-widget\">\n\t\t<h3>Find an eye doctor near you<\/h3>\n\t\t\n\t<form class=\"practice-search-form practice-search-form-widget\" action=\"https:\/\/www.optometrists.org\/practice-search\/results\/\" method=\"get\">\n\n\t\t<input type=\"hidden\" name=\"distance\" value=\"100\" class=\"practice-search-distance\">\n\t\t<input type=\"hidden\" name=\"page\" class=\"practice-search-page\">\n\t\t<input type=\"hidden\" name=\"address_latitude\"><input type=\"hidden\" name=\"address_longitude\">\n\n\t\t<input type=\"text\" name=\"address\" class=\"practice-search-address\" placeholder=\"City, Surburb or Address\" value=\"\">\n\n\t\t\n\t\t\t<input type=\"hidden\" name=\"distance\" value=\"100\" class=\"practice-search-distance\">\n\n\t\t\n\n\t\t<button type=\"submit\" class=\"practice-search-button\">\n\t\t\t\t\t\t\t\t\t<svg width=\"19\" height=\"19\" viewBox=\"0 0 19 19\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path fill-rule=\"evenodd\" clip-rule=\"evenodd\" d=\"M10.6796 0.130005C9.15708 0.130059 7.66615 0.5646 6.38198 1.38258C5.09781 2.20057 4.07373 3.36803 3.43004 4.74783C2.78634 6.12763 2.54976 7.66246 2.74808 9.17205C2.9464 10.6816 3.57139 12.1033 4.54964 13.27L0.729639 17.08C0.6364 17.1732 0.562439 17.2839 0.511979 17.4058C0.461519 17.5276 0.435547 17.6581 0.435547 17.79C0.435547 17.9219 0.461519 18.0524 0.511979 18.1743C0.562439 18.2961 0.6364 18.4068 0.729639 18.5C0.917942 18.6883 1.17334 18.7941 1.43964 18.7941C1.5715 18.7941 1.70207 18.7681 1.82389 18.7177C1.94571 18.6672 2.0564 18.5932 2.14964 18.5L5.99964 14.62C7.35406 15.6038 8.98566 16.1324 10.6596 16.13C12.7814 16.13 14.8162 15.2871 16.3165 13.7869C17.8168 12.2866 18.6596 10.2517 18.6596 8.13C18.6596 6.00827 17.8168 3.97344 16.3165 2.47315C14.8162 0.97286 12.7814 0.130005 10.6596 0.130005H10.6796ZM10.6796 14.13C9.49295 14.13 8.33291 13.7781 7.34622 13.1188C6.35952 12.4595 5.59049 11.5225 5.13636 10.4261C4.68224 9.32975 4.56342 8.12335 4.79493 6.95946C5.02644 5.79558 5.59788 4.72648 6.437 3.88736C7.27611 3.04825 8.34521 2.4768 9.5091 2.24529C10.673 2.01378 11.8794 2.1326 12.9757 2.58673C14.0721 3.04085 15.0092 3.80989 15.6685 4.79658C16.3277 5.78328 16.6796 6.94332 16.6796 8.13C16.6796 9.7213 16.0475 11.2474 14.9223 12.3726C13.7971 13.4979 12.2709 14.13 10.6796 14.13Z\" fill=\"#fff\"\/><\/svg>\n\t\t\t\t\t<\/button>\n\n\t\t<button type=\"button\" class=\"practice-search-use-my-location\">\n\t\t\tSearch near me\n\t\t<\/button>\n\n\n\t<\/form>\n\n\n\n\t\t<\/div>\n\n\t\n<h2><b>Is corneal cross-linking recommended for all patients?<\/b><\/h2>\n<p>Corneal cross-linking is generally recommended for patients in the beginning stages of keratoconus. This is generally due to the fact that the cornea at this point is not yet significantly irregularly shaped and any vision problems that have developed are generally not severe.<\/p>\n<p><b>When corneal cross-linking is performed in the early stages of keratoconus,\u00a0 this treatment can help to\u00a0 prevent further corneal distortions and the need for specialized contact lenses<\/b><\/p>\n<h2><b>Are you a candidate for corneal cross-linking?<\/b><\/h2>\n<p>To determine if you are a good candidate for a cross-linking procedure, your eye doctor will assess your cornea\u2019s shape and thickness using a <a href=\"https:\/\/www.optometrists.org\/a-guide-to-eye-turns\/what-is-corneal-topography\/\">corneal topography test<\/a>. This test provides a detailed, color-coded map of the layers and shape of your cornea.<\/p>\n<p>Your eye doctor will also measure your <a href=\"https:\/\/www.optometrists.org\/general-practice-optometry\/guide-to-eye-exams\/eye-exams\/what-is-a-visual-acuity-test\/\">visual acuity<\/a>, and examine your general eye health.<\/p>\n<h2><b>What to expect during your corneal cross-linking procedure<\/b><\/h2>\n<p>This outpatient procedure typically takes about an hour to complete, although the duration may vary depending on the procedure used.<\/p>\n<p>After the procedure, your eye doctor will place a special contact lens on your eye to protect your cornea while it heals. You will also be given a prescription for an <a href=\"https:\/\/www.optometrists.org\/dry-eye\/guide-to-eye-drops\/\">antibiotic and anti-inflammatory eye drop<\/a> to prevent infection and post-operative swelling.<\/p>\n<p><strong>To reduce your risk of complications, follow your eye doctor\u2019s instructions on self-care and take all your medications as prescribed.<\/strong><\/p>\n<p>Corneal cross-linking is an effective solution for patients with keratoconus.<\/p>\n<p><strong>LEARN MORE:\u00a0<\/strong>\u00a0Guide to<a href=\"https:\/\/www.optometrists.org\/general-practice-optometry\/guide-to-eye-conditions\/guide-to-corneal-diseases\/\"> Corneal Conditions<\/a><\/p>\n<p><strong><a rel=\"noopener\" href=\"https:\/\/www.optometrists.org\/practice-search\/\" target=\"_blank\" data-saferedirecturl=\"https:\/\/www.google.com\/url?q=https:\/\/www.optometrists.org\/practice-search\/&amp;source=gmail&amp;ust=1626760891136000&amp;usg=AFQjCNFHnklrD-k7GckF_J6pnDwdBDDa9Q\">Schedule an appointment<\/a> with an eye doctor for a comprehensive eye exam, and to discuss any questions you may have about treating your keratoconus<\/strong>.<\/p>\n<p><em>If you have been diagnosed with keratoconus, speak with your doctor for more information on how corneal cross linking (CXL) can help you.<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Keratoconus is a progressive eye disease that weakens the cornea and changes its structure \u2014 leading to vision problems and even vision loss.\u00a0 The cornea<\/p>\n","protected":false},"author":4,"featured_media":8837,"parent":7297,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"template-article.php","meta":{"footnotes":""},"categories":[],"tags":[84,225,228,216,204,432,173,136],"class_list":["post-8836","page","type-page","status-publish","has-post-thumbnail","hentry","tag-adults","tag-astigmatism","tag-cornea","tag-disease","tag-eye-drops","tag-keratoconus","tag-surgery","tag-vision-problem"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.9 - 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